DOP Session 3

DOP19-27

  • 17:30-18:30 Digital Oral Presentation Session 3: Translational science in IBD
    Room: C1-M2, Hall C, Bella Center
    Chairs: Peter Bossuyt, Bonheiden, Belgium
    Axel Dignass, Frankfurt, Germany
      17:30-17:36 DOP19: Spermidine treatment ameliorates experimental Colitis in vivo
    A. Niechcial1, E. Katkeviciute1, L. Hering1, M. Wawrzyniak1, M. Schwarzfischer1, K. Bäbler1, K. Attrot1, M. Scharl1, 2, M. R. Spalinger1
    1
    University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland, 2University of Zurich, Zurich Center for Integrative Human Physiology, Zurich, Switzerland
      17:36-17:42 DOP20: Drugs that modulate histone acetylation disrupt TGF-β- signalling and reduce collagen I expression in models of stricturing Crohn’s Disease
    A. Lewis1, A. Nijhuis1, G. Berti1, C. Felice2, R. Jeffrey1, S. Iqbal1, A. B. Pomeranc1, S. Aldelemi1, S. Mehta1, E. Giannoulatou3, R. Feakins4, A. Armuzzi2, J. O. Lindsay5, A. Silver1
    1
    Blizard Institute, Barts and The London School of Medicine & Dentistry, Centre for Genomics and Child Health, London, United Kingdom, 2IBD Unit, Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy, 3Victor Chang Cardiac Research Institute and 4St Vincent’s Clinical School, University of New South Wales, Sydney, Australia, 4Department of Histopathology, The Royal London Hospital, London, United Kingdom, 5Blizard Institute, Barts and The London School of Medicine & Dentistry, Centre for Immunobiology, London, United Kingdom
      17:42-17:48 DOP21: This abstract has been withdrawn.
      17:48-17:54 DOP22: UC-related and segment-specific properties of patient-derived colonic organoids
    K. Suzuki, H. Shimizu, M. Kawai, J. Takahashi, S. Anzai, A. Kawamoto, S. Nagata, Y. Hiraguri, S. Yui, K. Tsuchiya, T. Nakamura, K. Ohtsuka, K. Ohtsuka, R. Okamoto, M. Watanabe
    Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan
      17:54-18:00 DOP23: Myenteric plexitis and post-operative recurrence in Crohn’s Disease: The role of enteric glial cells and ICAM-1
    C. Le Berre1, J. Pabois1, T. Durand1, E. Durieu1, M. Rolli-Derkinderen1, C. Bossard2, J. Podevin3, M. Neunlist1, I. Neveu1, P. Naveilhan1, A. Bourreille1, 4
    1Nantes University Hospital, UMR Inserm 1235 - TENS, Gastroenterology department, Institut des Maladies de l’Appareil Digestif, Nantes, France, 2Nantes University Hospital, Pathology department, Nantes, France, 3Nantes University Hospital, Digestive surgery department, Institut des Maladies de l’Appareil Digestif, Nantes, France, 4Nantes University Hospital, CIC, INSERM 1413, Nantes, France
       18:00-18:06 DOP24: Intestinal acidification sensed by pH-sensing receptor GPR4 contributes to fibrogenesis
    B. Weder1, W. T. Van Haaften2, K. Baebler1, G. Rogler3, G. Dijkstra4, P. H. Imenez Silva5, Y. Wang5, C. De Vallière3, C. Wagner5, I. Frey-Wagner3, K. Seuwen6, P. Ruiz3, M. Hausmann3
    1University of Zurich, Zurich, Switzerland, 2University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, Netherlands, 3University Hospital Zurich, Department of Gastroenterology and Hepatology, Zurich, Switzerland, 4University of Groningen, Department of Gastroenterology and Hepatology, Groningen, Netherlands, 5University of Zurich, Institute of Physiology, Zurich, Switzerland, 6Novartis Institutes for Biomedical Research, Basel, Switzerland
       18:06-18:12 DOP25: Unravelling vedolizumab mechanism of action in Ulcerative Colitis
    M. Veny1, A. Garrido1, H. Bassolas-Molina1, M. C. Masamunt1, M. Esteller1, M. Arroyes1, A. M. Corraliza1, E. Tristán2, A. Fernández-Clotet1, I. Ordás1, E. Ricart1, M. Esteve2, J. Panés1, A. Salas1
    1IDIBAPS, Hospital Clínic, CIBERehd, Department of Gastroenterology, Barcelona, Spain, 2Hospital Universitari Mutua Terrassa, Department of Gastroenterology, Terrassa, Spain
      18:12-18:18 DOP26: Biological therapy increases NCR+ ILC3 levels in IBD patients
    B. Creyns1, 2, B. Verstockt2, 3, J. Cremer1, 2, V. Ballet3, M. Ferrante2, 3, S. Vermeire2, 3, J. Ceuppens1, G. Van Assche2, 3, C. Breynaert1
    1
    KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium, 2KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium, 3University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium
      18:18-18:24 DOP27: Late-breaking Abstract

Digital Oral Presentations
(as of January 2019)

  • DOP Session 1 Advances in IBD pathophysiology
    DOP01-09
    Room: C1 M1
    Chairs: Javier Gisbert, Madrid Spain
    Maximilian Waldner, Erlangen, Germany
    DOP Session 2 Mechanisms of intestinal inflammation
    DOP10-18
    Room: C1 M0
    Chairs: Loris Riccardo Lopetuso, Rome, Italy
    Britta Siegmund, Berlin, Germany
    DOP Session 3 Translational science in IBD
    DOP19-27
    Room: C1 M2
    Chairs: Peter Bossuyt, Bonheiden, Belgium
    Axel Dignass, Frankfurt, Germany
    DOP Session 4 Practicalities of IBD patient care
    DOP28-36
    Room: C1 M3
    Chairs: Uri Kopylov, Tel Aviv, Israel
    Fernando Magro, Porto, Portugal
    DOP Session 5 Old and new treatment
    DOP37-45
    Room: C1 M4-5
    Chairs: Paolo Gionchetti, Bologna, Italy
    Anne Strik, Amsterdam, The Netherlands
  • DOP Session 6 Novel treatments
    DOP46-54
    Room C1 M4-5
    Chairs: Marc Ferrante, Leuven, Belgium
    Gionata Fiorino, Rome, Italy
    DOP Session 7 Recent advances of biologic therapies
    DOP55-63
    Room: C1 M3
    Chairs: Filip Baert, Roeselare, Belgium
    Shomron Ben-Horin, Ramat Gan, Israel
    DOP Session 8 Intestinal healing
    DOP64-72
    Room: C1 M2
    Chairs: Raja Atreya, Erlangen, Germany
    Marietta Iacucci, Birmingham, United Kingdom
    DOP Session 9 Surgery and IBD
    DOP73-81
    Room: C1 M1
    Chairs: Paulo Kotze, Curitiba, Brazil
    TBC
    DOP Session 10 Clinical epidemiology
    DOP82-90
    Room: C1 M0
    Chairs: Stefanos Bonovas, Milan, Italy
    Johan Burisch, Copenhagen, Denmark