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P088. The comparison of three types of capsule endoscopes by small bowel transit time in patients with Crohn's disease

A. Derovs1, J. Derova2, J. Pokrotnieks1

1P.Stradin Clinical University hospital, Riga, Latvia; 2Latvian Maritime Medical Centre, Riga, Latvia

Background: The impact of small bowel transit time (SBTT) on diagnostic yield during capsule endoscopy (CE) is very significant. Delayed small bowel transit time in patients with Crohn's disease can considerably affect the efficacy of VCE.

Aim of study: This study was designed to evaluate SBTT in patients with Crohn's disease using different types of CE systems.

Material and Methods: Patients with Crohn's disease and similar bowel habits (1–2× per day), who underwent CE, were randomly chosen from the database. All the patients were divided into three groups by capsule endoscope type: Olympus Endocapsule, Given Imaging PillCam and OMOM Capsule endoscope. Patients with constipations or diarrhea were not enrolled in the study to avoid bias results. The effect of third possible impact factor (such as age, sex, gastric transit time) on SBTT was also evaluated. Statistic calculations were performed using SPSS ver. 16.

Results: In total from database of 200 patients, 39 cases were analyzed. From them 10 pts. underwent CE with Olympus Endocapsule, 10 pts. – with Given Imaging PillCam and 19 pts. – with OMOM Capsule endoscope. Prevalence of males and females and patients' age were similar in all groups. Average patients' age were in range from 31.4 to 38.4 (±15.1). SBTT in Given Imaging PillCam group were from 150 to 388 min. (mean 254.1±76.5). SBTT in Olympus Endocapsule group were from 194 to 502 min. (mean 326.8±135.1). SBTT in OMOM Capsule endoscope group were from 82 to 357 min. (mean 255.7±79.7). Capsule didn't reach the ceacum in 6 cases using Olympus Endocapsule system, in 3 cases using OMOM Capsule endoscope and in 0 cases using Given Imaging PillCam. In all cases, when capsule didn't reach the ceacum, gastric transit time (GTT) was evaluated. No statistically significant correlation between SBTT and GTT was observed. The statistically significant difference between SBTT in different types of CE system was not observed. The effect of third impact factor was not established.

Conclusions: Small bowel transit time does not depend from capsule endoscopy system. However such big amount of unsuccessful CE, when CE did not reach the ceacum and the relatively longer mean time using Olympus Endocapsule system shows controversial tendency for using this system in patients with Crohn's disease.

Acknowledgements: This study was made with European Social Fund (ESF) support.