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P338. Impact of inflammatory bowel disease on sexual function

L. Marín1,2, M. Mañosa1,3, J. Gordillo2, Y. Zabana1,3, E. Cabré1,3, E. Garcia Planella2, E. Domènech1,3

1Hospital Universitari Germans Trias i Pujol, Badalona, Spain; 2Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 3CIBERehd, Barcelona, Spain

Quality of life (QoL) is usually disturbed in IBD. Sexuality is an important part of QoL but it is not addressed in most generic or IBD-specific QoL questionnaires, and IBD activity indexes. As a consequence, the specific impact of IBD on patient's sexuality is poorly known.

Aims: To evaluate the prevalence of sexual dysfunction among IBD patients as compared to controls, and to identify predisposing factors.

Material and Methods: A specific questionnaire, together with a stamped envelop for response, was sent to 1,528 IBD patients of 25 to 65 years of age who were identified from the IBD databases of the two participating centres. Patients were asked to provide a control without IBD but of the same gender and age, who had to fill in a specific questionnaire for controls. The questionnaire assessed the patients' perception of the impact of IBD on their sexuality and the factors associated to a sexual disturbance; moreover, both patients' and controls' questionnaires allowed the calculation of the Erectile Function International Index (EFII) and the Female Sexual Function Index (FSFI).

Results: Four hundred and five questionnaires were returned and 63 did not reach the addressee, accounting for a 30% of response. After excluding those that were unsuccessfully completed, 202 female patients/127 controls and 153 male patients/73 controls were included for analysis. Half of the female patients and one third of male patients considered that both sexual desire and satisfaction worsened after IBD diagnosis. As compared to controls, no differences were found in any domain of the EFII, but women with IBD had significantly lower scores in all the domains of the FSFI. Independent predictors of sexual dysfunction among IBD women were Crohn's disease (as compared to ulcerative colitis) and the use of corticosteroids. In men with IBD, sexual dysfunction was associated to depression or diabetes, in the multivariate analysis.

Conclusions: A disturbed of sexual function is perceived by a greater proportion of women than men with IBD. When present, sexual dysfunction seems to be associated to IBD-related features in women but not in men.