Search in the Abstract Database

Search Abstracts 2011

* = Presenting author

P353. Influence of frozen food consumption in risk for developing inflammatory bowel disease

R. Souto, M. Barreiro-de Acosta, A. Alvarez, M. Iglesias, A. Lorenzo, J. Dominguez-Muñoz

University Hospital, Santiago de Compostela, Spain

Aim: Environmental risk factors playing a causative role in inflammatory bowel disease (IBD) remain largely unknown. Recently, based in the cold chain hypothesis it has been suggested that refrigerated food could be involved in IBD, especially Crohn's disease (CD, development. The aim of this study was to evaluate the influence of frozen food consumption in the risk for IBD.

Methods: We performed a prospective, consecutive case–control study of all patients over 18 years diagnosed of CD and ulcerative colitis (UC) in the last 8 years. As controls we included healthy, unrelated individuals, matched by ethnic, sex and age, with no family history of IBD. All patients and healthy were interviewed by the same interviewer about dietetic habits before IBD diagnosis including frequency of consumption of frozen food, differing between domestic frozen food and manufacturers frozen food. The consumption was quantified in number of portions by unit of time (day, week or mouth, in dependence of different foods). Results are shown as OR 95%CI and analyzed by Mann-Whitney U test.

Results: We studied 242 consecutive patients with recent diagnosis of IBD, 105 with CD and 137 with UC. Gender distribution was 124 (51%) female and 118 (49%) male, mean age 39 (18–77) years, and 242 controls matched by sex and age. We did not observed differences between cases and controls in frozen consumption (p = n.s). After analyzing separately CD and UC neither we observed differences in the frozen food consumption before the diagnosis (p = n.s). No differences between cases and controls were shown attending to the consumption of food with different type of refrigeration (manufacturer or domestic) (p = n.s).

Conclusion: Frozen food consumption before diagnosis seems not play any role in development neither in CD nor in UC. More studies are needed in order to evaluate the potential effects of frozen food in IBD.