Search in the Abstract Database

Search Abstracts 2011

* = Presenting author

P067. Comparison of wireless capsule endoscopy and enteroclysis in the work-out of patients with established and suspected small bowel Crohn's disease

N. Viazis, A. Keyoglou, E. Saprikis, E. Anastasopoulos, G. Zacharakis, D. Karamanolis

2nd Department of Gastroenterology, Evangelismos Hospital, Athens, Greece

Aim: The aim of this study was to prospectively compare the diagnostic yield of wireless capsule endoscopy (WCE) and enteroclysis in the detection of Crohn's disease (CD) of the small bowel.

Materials and Methods: Fifty-eight patients with known CD (group 1) suspected to have more extensive small-bowel involvement and 52 patients, who were suspected to suffer from CD but did not have an earlier history of it (group 2) were prospectively evaluated with enteroclysis and WCE. Each examiner was blinded to the results of other investigations.

Results: Enteroclysis was unsuccessful in 4 patients from group 1 and 12 patients from group 2. In group 1, abnormal findings consistent with CD were detected in 40 patients by using WCE and in 22 patients by using enteroclysis, out of the total 54, at per-protocol analysis (74.1% vs. 40.7%, p < 0.05). Of the 22 patients who had ileal CD on enteroclysis, 6 had more extensive small-bowel disease, which was detected only by WCE. In group 2, WCE showed findings consistent with CD in 26 out of the 40 patients, in contrast with enteroclysis, which was positive for CD in only 12 out of the 40 patients (65% vs. 30%, p < 0.05). Six more patients had findings compatible with CD on WCE, but they failed their enteroclysis. Overall, a new diagnosis of CD was made in 32 patients.

Conclusion: WCE has a higher diagnostic yield than enteroclysis in the detection of CD of the small bowel, both in patients with known and newly suspected CD.