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DOP027. Work disability in patients with inflammatory bowel diseases. Final report from two referral centers

M. Mandel1, A. Balint2, B. Lovasz1, L. Kiss1, P.A. Golovics1, Z. Vegh1, K. Farkas2, T. Molnar2, A. Mohas1, B. Szilagyi1, P. Lakatos1, 1Semmelweis University, 1st Department of Medicine, Budapest, Hungary, 2University of Szeged, 1st Department of Medicine, Szeged, Hungary

Background

To compare the work disability (WD) rate in inflammatory bowel disease (IBD) patients, with the WD rate in the background population, and to assess whether clinical or demographic factors are associated with WD.

Methods

Data of 384 (male/female 170/214, CD/UC: 224/160, median age at onset: 27–1 and 30.7 years, duration: 9.2 and 10.3 years) consecutive patients with at least one-year disease duration were included. WD data were collected by questionnaire. Data on disability pension (DP) in the background population were retrieved from public databases (ONYF). We calculated overall and age-standardised relative risks (RR) for DP. Logistic regression analysis was used to examine predictive factors.

Results

The overall DP rate in this referral population was 35.2% with partial disability in 25.2%. 53% of the patients with partial or full DP felt that they could work, 40% had a part time job. Overall, full DP was more prevalent in IBD (RR: 1.56, 95% CI: 1.13–2.17) and CD (RR: 1.79, 95% CI: 1.20–2.66) but not in ulcerative colitis (RR: 1.14, 95% CI: 0.62–2.07) compared to the background population and in CD compared to UC (RR: 1.82, 95% CI: 1.17–2.82). The DP rate increased gradually parallel with the age groups (from 20.5% in the <35-year-olds to 62.7% in the 51–62-year olds). The RR for full DP was highest in patients with an age <35 years and 35–40-years (RR: 11.1 and 6.4), while >46 years-old patients had no increased RR. Previous surgery/colectomy (OR: 5.03, 95% CI: 3.09–8.21), long disease duration (OR: 3.48, 95% CI: 2.24–5.40) and presence of arthralgia (OR: 3.47, 95% CI: 2.20–5.48) but not disease phenotype, exposure to steroids, need for azathioprine or biological were associated with an increased risk for DP.

Conclusion

IBD patients are at increased risk for DP as compared with the background population. The youngest patients had the highest risk. Previous surgery and presence of arthralgia was identified as risk factor for DP.