Search in the Abstract Database

Abstracts Search 2014

* = Presenting author

P132. Study of intestinal parasitic infections and risk factors among patients suffering from inflammatory bowel disease in Alexandria, Egypt

F.I.M. Hassanein3, Z.M. Shaibat El-Hamd2, S.A. El-Masry2, E.A. Ahmed1, A.A. Hassan2, 1Alexandria university, Internal medicine-gastroenterology unit, Alexandria, Egypt, 2High Institute of Public Health, Department of Tropical Health, Parasitology and Medical Entomology, Alexandria, Egypt, 3Faculty of Pharmacy and Drug Manufacturing-Pharos University, Microbiology and Immunology, Alexandria, Egypt

Background

To study intestinal parasitic infections and risk factors among patients with inflammatory bowel disease (IBD) and their controls.

Methods

Stool specimens were collected from 40 cases suffering from IBD previously diagnosed on treatment attending the Internal Medicine Department, Gastroenterology Unit in Alexandria Main University Hospital, Faculty of Medicine and the same among controls. The specimens were subjected to cultures, stains for fresh smears, kato-katz technique and concentration technique.

Results

The highest % of infections was detected among IBD including Microsporidia, Cryptosporidium then Blastocystis hominis as compared to controls. Concerning host factors (gender, age, occupation, educational, socioeconomic and personal hygiene levels), IBD cases showed higher risk of infection in comparison to control group. This was expressed by the higher odds ratio regarding gender and the age groups from 10 years old to less than 50 years old, highly educated, professional, urban residents, low crowding index, those who did not use roof water tank and those who had high socioeconomic and personal hygiene levels. Also, patients who consumed immunosuppressive drugs in combination with 5ASA, corticosteroid and biological treatment showed the highest percentage of parasitic infection among those who had >3 parasites.

Conclusion

Host factors and immunosuppressive medications showed high risk for the opportunistic parasitic infections among IBD patients as compared to the controls.