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P201. Is depression associated with more emergency visits in inflammatory bowel disease?

G. Sirin, A. Celebi, O. Senturk, S. Hülagu, Kocaeli University, Gastroenterology, Kocaeli, Turkey

Background

Anxiety and depression are highly prevalent in Inflammatory Bowel Disease (IBD) patients, but their role in the clinical course of the disease is unknown. We was aimed that to investigate the influence of anxiety and depression symptoms in emergency visits and hospitalizations in patients with IBD.

Methods

We conducted a prospective observational cohort study at the Kocaeli University Gastroenterology department between 2010–2013. The cohort consisted of consecutive patients with Crohn's disease (CD) and ulcerative colitis (UC) who enrollment our IBD Outpatient Unit. In order to identify anxiety or depression, a psychological investigation was performed at baseline in all of them by the Beck's Anxiety and Depression scale. In order to assess the clinical course of IBD, all emergency visits and hospitalizations related with IBD over a follow-up period of 24 months were recorded. Results are shown as RR and 95% CI and analysed by Poisson Regression.

Results

381 patients were included (203 male, mean age 42 years, ages ranging from 18 to 82 years), 126 (33.1%) patients with CD and 255 (66.9%) with UC. At baseline evaluation, anxiety and depression symptoms were present in 25 (20%) and 144 (30%) patients respectively. The mean of emergency visits was 1.24 (SD: 1.82, range 1–12) and for hospitalizations it was 0.84 (SD: 0.96, range 0–11). After a follow up of 24 months, both depression at baseline was a risk factor for more emergency visits (RR: 1.38, 95% CI: 1.24–1.76) and anxiety (RR: 1.31, 95% CI: 1.21–1.40).

Conclusion

An important number of IBD patients have anxiety or depressive symptoms. Depression and anxiety seems to be as risk factors for more emergency visits in the following months.