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P389. Patients' self-assessment of their knowledge about ulcerative colitis indicates level of adherence

W. Kruis1, H. Grümmer2, B. Gerhard3, S. Blau4, M. Düffelmeyer5, S. Ceplis-Kastner6, B. Reimers7, 1Evangelisches Krankenhaus Kalk, University of Cologne, Köln, Germany, 2Praxis für Innere Medizin, Facharzt für Innere Medizin, Potsdam, Germany, 3Praxis für Innere Medizin, Fachärztin für Innere Medizin, Berlin-Hellersdorf, Germany, 4Praxis für Innere Medizin, Fachärztin für Innere Medizin, Frakfurt am Main, Germany, 5IOMTech GmbH, Statistics, Berlin, Germany, 6Ferring Arzneimittel GmbH, Pharmaceutical Department, Kiel, Germany, 7Ferring Arzneimittel GmbH, Specialty Care, Kiel, Germany


It is a general belief that informed patients show better adherence to the treatment. But who assesses the degree of information? The aim of this study was to clarify if patients are able to realistically self-assess their knowledge about their disease and if better informed patients show a higher compliance.


A total of 343 mesalazine-treated with ulcerative colitis (UC) patients (48.9% females), aged between 16–82 years were included into the interim analysis of a prospective study conducted in 113 specialized private GI practices all over Germany. Compliance was rated by the patients themselves using a visual analogue scale (VAS) ranging from 0 (I have taken all medication correctly) to 10 (I have taken no medication). Knowledge about UC was tested by 9 questions such as “is UC infectious” or “is there a special diet for UC”. Self-assessment of knowledge was graded as very good, good, moderate, small, don't know. In this post-hoc analysis three groups of patients were defined: Group I gave 7–9 correct answers, group II 4–6, and group III 0–3.


A correct answer to all 9 questions was given by 4% of the patients while no correct answers were given by 5% of the patients; 51% answered between 4 and 6 questions correctly. Self-assessment of good or very good knowledge was correlated with the number of correct answers in the questionnaire. Though it was rather consistent, self assessment matched best in group I (93.71% of the patients), in 84.79% of the patients of group II, and in 60.94% of the patients of group III. Quality of self-assessment showed no relevant differences in relationship to gender, age or duration of the disease. The number of correctly answered questions was related to compliance: Group I 1.76±2.73 (VAS mean±SD), group II 1.86±2.56; group III 2.18±2.55.


In general, patients are well informed about their disease and are able to self-assess their level of information. Better information supports better compliance. To improve adherence with the treatment patients should be asked for their knowledge of the disease. Supplementary information is needed in patients who rate their grade of information low.