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P479. Feasibility and utility of a web-based self-reporting symptoms diary of Crohn's disease

E.S. Kim1, K.B. Cho1, B.I. Jang2, S.W. Jeon3, M.K. Jung3, E.Y. Kim4, K.O. Kim2, K.S. Park1, C.H. Yang5, 1Keimyung University School of Medicine, Internal Medicine, Daegu, Korea, Republic of, 2Yeungnam University College of Medicine, Internal Medicine, Daegu, Korea, Republic of, 3Kyungpook National University School of Medicine, Internal Medicine, Daegu, Korea, Republic of, 4Catholic University of Daegu School of Medicine, Internal Medicine, Daegu, Korea, Republic of, 5Dongguk University College of Medicine, Division of gastroenterology and Hepatology, department of Internal Medicine, Kyungju, Korea, Republic of

Background

Crohn's Disease Acitivity Index (CDAI) is known to be complex, time-consuming, and impractical. There are inherent deviations, such as recall bias, in data collected through CDAI. Therefore, it is necessary to develop simpler, more reliable and verifiable data collecting system for patients with CD. The aim of this study was to evaluate the feasibility of using a newly-developed web-based self-reporting symptoms diary of CD (CDSD).

Methods

CDSD consisted of 5 clinical items (general well being, abdominal pain, number of liquid stools, abdominal mass, and complications) which could be easily recorded through online web site (www.CDSD.or.kr). Images were inserted to help patients better understand the complications. All patients were asked to visit and record their symptoms on weekly bases. We estimated the number of web site visits and assessed demographic and clinical data as potential predictive factors for high compliance to CDSD (>5 visits).

Results

Overall, 186 were included in the study (male 131, mean age 29.1±10.4 years). During mean follow-up period 209.2±67.8 days, the median number of visits was 5 (1–66 times). One hundred twelve (60.2%) and 60 (32.3%) recorded CDSD at least 2 times and 10 times, respectively. Low level of education, employed state, small bowel location, and use of thiopurine tended to be related with higher visits to CDSD. In multivariate analysis, low level of education (OR 2.22, 95% CI 1.14–4.35, p = 0.019) and small bowel location (OR 4.65, 95% CI 2.01–10.75, p < 0.001) were identified as significantly independent predictive factors for high compliance.

Conclusion

This study supports the feasibility of a newly-developed online collecting data system. Compliance to this system is related with education level of patients and small bowel location of disease.