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P593. The incidence and natural history of paediatric Inflammatory Bowel Disease Unclassified in Scotland


Inflammatory Bowel Disease Unclassified (IBDU) accounts for ∼




of paediatric IBD (PIBD) and remains a common IBD subtype at diagnosis in PIBD. The natural history of IBDU includes potential evolution to Crohn's disease (CD) or ulcerative colitis (UC). Few epidemiologically robust studies of IBDU exist. We aimed to describe the incidence and the natural history of paediatric IBDU in a population-based cohort.


The incidence of IBDU was collected over a 10-year period (01/03–12/12) using mainly prospective data collection from the two largest Scottish paediatric gastroenterology networks, which provide care for 681,176 children <16 years (74.4% of age relevant Scottish population). Demographics and details of diagnostic investigation and follow up data were obtained until study end (31.10.13; unless prior transition or emigration) to ascertain reclassification of IBD subtype, clinical progress and outcome at last follow up. Incidence rates and trends were calculated using publicly available population data and statistics generated using Poisson regression.

  • Written by:

    F.L. Cameron1, P. Henderson1, R.K. Russell2, D.C. Wilson1, 1University of Edinburgh, Child Life and Health, Edinburgh, United Kingdom, 2Royal Hospital for Sick Children, Paediatric Gastroenterology, Glasgow, United Kingdom