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P628. Epidemiology and hospital resources use in the treatment of ulcerative colitis at gastroenterology units in Spain (EPICURE Study)

Background

To estimate the prevalence and incidence of ulcerative colitis (UC) according to ECCO guidelines at hospital Gastroenterology (GE) units in Spain (primary objective) and to assess the use of hospital resources (characteristics and facilities) for the management of patients with UC in Spain (secondary objective).

Methods

A retrospective, multicenter, epidemiological, cross-sectional study (EPICURE study) was conducted. At selected Spanish sites, adult patients with confirmed UC at any stage or extent of disease, and in follow-up, were randomly invited to participate. Analysis of data from hospital registries and records from UC patients being attended in 2011 is presented herein. The prevalence of UC in GE units was calculated as the total UC patients divided by the total inhabitants covered in those sites. Incidence was defined as the number of new UC cases during 2011 divided by the total inhabitants covered in those sites. The study was sponsored by Abbvie.

Results

In 2011, about 42,000 patients were attended for UC in GE units in Spain with a prevalence rate of 88.6 UC cases [95% CI: 87.68, 89.54]/100,000 inhabitants. During 2011, the incidence rate for UC was 5.8 cases [95% CI: 5.60, 6.08]/100,000 inhabitants. A median of 5% patients being attended for UC were hospitalized in the 55 units analyzed so far in Spain in 2011. There were a total of 1,006 hospitalizations due to UC (median: 14 per GE unit). The median length of hospital stay was 8 days. Around 259 (0.62%) UC patients received colectomy at these units in 2011. Almost one third (28.2%) were emergency colectomies. The median stay at hospital for colectomy due to UC was 14 days.

Most hospitals had specific monographic IBD units (87.3%) and colorectal surgeons (92.7%). There was no statistically significant relationship between the presence of IBD units and the number of patients attended or the percentage of emergency colectomies performed, but the average length of hospital stay after colectomy for UC was significantly (p = 0.0150) decreased if a surgical specialized unit was available.

Conclusion

Our study provides the first national data on the prevalence and incidence of UC in GE units in Spain. Hospitalisation and surgical burden associated with UC was low.

  • Written by:

    I. Marin-Jimenez1, C. Saro2, V. Díaz3, M. Barreiro-de Acosta4, M. Gómez-García5, N. Borruel6, A. Gutierrez7, 1Hospital General Universitario Gregorio Marañón, Gastroenterology section - Digestive System Medicine Department, Madrid, Spain, 2Hospital de Cabueñes, Digestive Department, Gijon, Spain, 3AbbVie Farmacéutica S.L.U., Inmunology, Madrid, Spain, 4Hospital Clínico Universitario, Gastroenterology - Inflammatory Bowel Disease Unit, Santiago de Compostela, Spain, 5Hospital Universitario Virgen de las Nieves, Digestive Department, Granada, Spain, 6Hospital Vall d'Hebrón, Digestive Department, Barcelona, Spain, 7Hospital General Universitario, Digestive Medicine Department, Alicante, Spain