P635. Comorbidity related hospitalizations in inflammatory bowel disease patients
M. Crncevic Urek, S. Cukovic-Cavka, R. Prijic, N. Turk, M. Brinar, Z. Krznaric, B. Vucelic, University Hospital Centre Zagreb, Division of Gastroenterology and Hepatology, Zagreb, Croatia
Inflammatory bowel diseases (IBD) are chronic states associated with number of life-threatening comorbidities. In this study we analysed the major reasons for comorbidity related hospitalizations among IBD patients (pts) treated in tertiary referral centre.
Data from hospital records from 2011 to 2013 were collected. Study included 257 IBD pts; 69 with ulcerative colitis (UC) and 188 with Crohn's disease (CD). Pts were analysed according to age, gender, activity, localization and disease behaviour (Montreal classification). We compared number and characteristics of hospitalizations due to IBD and comorbidity related hospitalizations. Comorbidities as the reason for hospitalizations were grouped as follows: cardiovascular, malignancy, infections, urological complications and others. The influence of immunosuppression and characteristics of IBD on comorbidity related hospitalizations were also analysed.
188 pts with CD and 69 UC pts (45.74% male, 54.26% female, mean age 23.04, range 1–63 yrs) were included into the study. Hospitalizations were divided into IBD-hospitalizations and comorbidity related hospitalizations. The overall number of hospitalizations in UC and CD group was 506, among them 425 (83.98%) due to IBD (relapse or reevaluation) and 81 (16%) due to comorbitidies. Cardiovascular diseases as the reason for hospitalizations were recognized in 2% CD pts and 8%UC pts; urological reasons in 15%CD and 4% UC pts; the overall percentage of malignancy was 1.3% (5 pts - 3 CD pts, 2 UC pts); infections in 20%CD and 16% UC pts and 16% for other reasons. Malignancy included 1 colorectal cancer, 1 multiple myeloma, 2 renal cancer, 1 papillar thyroid cancer. The significant number of CD pts (29) were hospitalized due to urological reasons that might be explained with penetrating behaviour of disease to surrounding organs. Logistic regression model isolated following variables as important for increased comorbidity hospitalizations: ileocolonic localization of CD (p = 0.067), extensive colitis in UC pts (p = 0.088), age 16–60 yrs in both groups (CD p = 0.036, UC p = 0.430). Immunosuppression (classic and antiTNF) did not influence comorbidity hospitalizations (CD p = 0.319, UC p = 0.772).
- Written by: the importance of urological complications in Crohn's disease
- Posted in: Poster presentations: Epidemiology (2014)