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P641. Anxiety and depression in a prospective cohort of inflammatory bowel disease patients in Ireland


Depression is one of the more recognised illnesses that has been associated with chronic diseases and projected to be the second worldwide condition by 2020. Both anxiety and depression links to Inflammatory bowel disease (IBD) have been the focus of many studied over the past decade.

In our study, we evaluated the level of hospital anxiety and depression scale (HADS) in a homogenous population cohort of Irish IBD patients, in their second decade of IBD diagnosis.


IBD patients who were prospectively diagnosed 1991–1992 in the greater Dublin area were included in twenty year follow up study. For this part of the study they were asked to complete the HADS questionnaire, disease activity index, medical and surgical IBD history, and to express their interest in IBD information.


There were 100 questionnaires analysed after excluding 5 (2 IC and 3 UC to CD). Of those 64 patients had UC and 36 had CD. Over all there was no gender difference in anxiety or depression in IBD in general, however when evaluating CD separately from UC depression appeared significantly more than anxiety in each subgroup p < 0.001. UC patients at younger age had significantly higher anxiety and depression of 0.012 and 0.013 respectively and were more interested in IBD information than older UC patients. IBD disease activity had greater effect on anxiety than depression, that was more marked in UC than CD, whereas IBD disease course and hospitalisation didn't seem to have an effect on anxiety or depression.


IBD was proved to be associated with anxiety and depression in Ireland. Patients still remain anxious despite many years of diagnosis and likely to be interested in seeking information at younger age particularly if they had UC. Patient education and counselling would help addressing anxiety and depression by their physician and perhaps psychologist for better outcomes.

  • Written by:

    M. Shuhaibar1,2, C. O'Morain2, 1Adelaide and Meath Hospital, Department of Gastroenterology/Clinical Medicine, Dublin, Ireland, 2Department of Clinical Medicine/Trinity College Dublin, Ireland