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* = Presenting author

P103 Assessment of QOL using internet web system in Japanese patients with Inflammatory Bowel Disease: The 3I survey

Y. Toya*, S. Yanai, T. Matsumoto

Iwate Medical University, Division of Gastroenterology, Department of Internal Medicine, Morioka, Japan

Background

Little is known about the QOL of patients with inflammatory bowel disease (IBD) in Japan. The aim of this survey was to compare the current living conditions and QOL between patients with IBD and healthy people in Japan, using a questionnaire through Internet-Web system (3I survey).

Methods

Through the Internet, we asked 464 patients with Crohn's disease (CD), 360 patients with ulcerative colitis (UC) and 4100 healthy controls (HC) for a questionnaire including SF-8 to. The survey was conducted until the predetermined numbers of CD patients (120), UC patients (120) and HCs (240) could be achieved.

Results

Responses to the questionnaire were obtained from 120 CD patients, 120 UC patients, and 240 HCs. While there were significant differences in gender with male predominance in CD patients (73%) and UC patients (76%) when compared to HCs (57%), other demographics were no different among the three groups. The marriage rate in adults was significantly lower in CD group than in UC group and HCs. The mean annual income and the unemployment rate were also significantly lower in CD group than in the other two groups. QOL assessment by means of SF-8 revealed that five of the eight items showed significantly lower values in CD and UC groups than HCs. Furthermore, the five items were lower in CD group than in UC group. The overall analysis of CD and UC patients showed that there was a significant and negative correlation between each score of SF-8 and the 4-grade degree of symptoms (diarrhea and abdominal pain).

Conclusion

The Results of the survey suggested that the marriage rate and income are lower in Japanese patients with IBD, and this is especially the case for patients with CD. The QOL seems to be disturbed in Japanese patients with IBD, presumably due to abdominal symptoms.