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* = Presenting author

P138 Health Quality and Sexual Dysfunction in Turkish IBD Patients

M. Törüner*1, E. Ates2, C. Kalkan1, F. Karakaya1, H. Cetinkaya1, I. Soykan1

1Ankara University School of Medicine, Dept. Gastroenterology, Ankara, Turkey, 2Ankara University School of Medicine, Dept. Internal Medicine, Ankara, Turkey

Background

In Inflammatory Bowel Diseases (IBD) patients, there is an impaired quality of life (QoL) and sexual dysfunction. However, there might be some differences between countries because of different cultures and socio-economical alterations.

In this study, we aimed to evaluate the frequency of sexual dysfunction and the level of QoL in Turkish IBD patients.

Methods

In this study, we evaluated 112 IBD patients (64 patients with Ulcerative colitis: 57%) and 42 control subjects. All patients and control subjects were asked to fill three questionnaires (SF 36, Hospital Anxiety and Depression Scales (HAD-A and HAD-D), Arizona Sexual Experience Scale (ASEX)). Demographic characteristics are collected and disease activity was determined for each patient.

Results

In all evaluated patients, demographic data (age, disease activity, gender, education) was not differ from each other. Inpatient subjects had more severe disease than outpatient subjects as expected.

Smokers and ex-smokers were more frequent in Crohn's Disease group whereas there were no difference in alcohol consumption.

HAD-D scores were significantly higher in both Ulcerative colitis (UC) and Crohn's Disease (CD) patients when compared to control group. However, there was no difference between 2 disease groups. HAD-A scores were significantly higher in CD group when compared to UC and control subjects. There was no difference between UC and control group. Female patients had more anxiety scores, there were no correlation between depression scores and gender. Both HAD-D and HAD-A scores are positively correlated with educational status.

When SF-36 scores were evaluated, in both disease groups, scores were worse than control group as expected, whereas there was no difference between UC and CD patients.

Sexual dysfunction frequency was different between three groups, however, patients with more severe disease had more sexual dysfunction.

Conclusion

In conclusion, we found no difference between CD/UC groups and control group for sexual dysfunction scores. However, with the increase in disease activity, both UC and CD patients have more sexual dysfunction than control subjects.

Disease activity was also found to be positively correlated by anxiety and depression score whereas, there was a negative correlation between disease activity and QoL. Anxiety and depression were seen more frequently in highly educated subgroup.