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* = Presenting author

P162 Is Sensorineural Hearing Loss Frequent in Patients With Inflammatory Bowel Disease? Preliminary Results Of Ongoing Study

G. Sirin*1, O. Senturk1, A. Celebi1, S. Sirin2, S. Hulagu1

1Kocaeli University, Gastroenterology, Kocaeli, Turkey, 2Seka State Hospital, ENT Department, Kocaeli, Turkey

Background

Sensorineural hearing loss (SHS) has been reported in many autoimmune diseases before. Inflammatory bowel diseases (IBD) have a lot of characteristics of autoimmune diseases. But there are little data about SHS frequency in these patient population.

Methods

We conducted a prospective blinded comparative study to be continued over a 2 year period in three large medical centers in Kocaeli. IBD patients and controls underwent a complete otorhinolaryngeal examination include an eudiometry test. Any participant who has current use or history of take an ototoxic medication or recurrent either existent ear infections was excluded from the study.

Results

Up to the present 84 participants (63 patients and 21 controls) were included. 36 (57.1%) had Crohn's disease (CD) and 27 (42.9%) had ulcerative colitis (UC). Mean age was 33 ± 16. 52.4% were males and 63.5% of the patients were presently hospitalized due to IBD exacerbation. 11/63 of the IBD patients complained of hearing loss since first IBD diagnosis and 5 had current hearing disabilities. Audiometric examination revealed that any hearing loss (mild to severe) was found in 13 (20.1%) of the IBD population, compared to 1 (4.7%) of the control group (p=0.05). was Major hearing deficiency type was sensironeural ones. Hearing loss was present in 5/15 (30%) of patients with extra intestinal manifestation(s) (EIM), compared to 2/36 who did not have EIM (p<0.01).

Conclusion

Sensironeural type hearing loss may be another EIM of IBD. Early complete hearing evaluation should be recommended to IBD patients especially one's who have other EIM's.