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* = Presenting author

P198 Ionizing radiation exposure in patients with inflammatory bowel disease: Are we overexposing our patients?

M. Fekih*1, A. Laabidi2, L. Kallel2, R. Ben Jemaa2, N. Ben Mustapha2, M. Serghini2, J. Boubaker2, A. Filali2

1La Rabta hospital , Gastro enterology"A", Bab Saadoun, Tunisia, 2La Rabta hospital, Gastro enterology"A", Bab Saadoun, Tunisia

Background

Crohn's disease (CD) is a lifelong condition. Multiple imaging investigations are often performed during follow-up. This could cause overexposure to radiation. The aim of our study was to determine mean radiation dose in patients with at least a 5-year course of CD and to determine possible risk factors associated with exposure to high doses of radiation

Methods

We conducted a retrospective study including patients who's CD. Epidemiologic features of patients, characteristics of the disease, and types of imaging investigations that were performed during follow-up and cumulative radiation effective dose were determined. Risk factors associated with exposure to high doses of radiation were then, determined.

Results

One hundred sixty seven patients were included. There were 92 males (55.1%) and 75 females (44.9%) with mean age at diagnosis of 31.4 years (11 - 75 years). Global radiation dose was 18.81 mSv (0.02 - 120.02). Twenty seven patients (16.2%) were exposed to more than 35 mSv and 4 patients (2.4%) had an exposure of more than 75 mSv. Use of Infliximab, age at disease onset < 24 years old and number of flares > 8 were independent risk factors of radiation exposure more than 35 mSv with Odds ratios (OR) 2.543 ; 1.631 and 3.158 respectively. Similarly, use of Infliximab and number of flares > 8 were independent risk factors of radiation exposure more than 75 mSv with OR 4.256 and 7.012 respectively.

Conclusion

Radiation risk seems to be increased with severe course of CD. Both referring physicians and radiologists have the responsibility to minimize radiation exposure. Entero-magnetic resonance imaging (Entero-MRI) may reduce this risk.