P211 Gender-related differences in work productivity impairment and quality of life in Inflammatory Bowel Disease (IBD): A cross-sectional survey from Southern Italy
M. Cappello*, R. Alloro, M. Mazza, M. Mendolaro, P.L. Almasio, A. Craxì
University of Palermo, Gastroenterology Section, DiBiMis, Palermo, Italy
IBD are chronic conditions affecting young people with a negative impact on their major life activities, such as school, work, self-care, and quality of life. Published literature has reported higher rate of unemployment, sick leave and working disability. Data on gender influence are scanty, especially in mediterranean countries. Aim of our study was to compare working impairment and quality of life between female and male patients with IBD followed-up in a referral center from southern Italy.
102 patients with IBD (53 females, 49 males) consecutively observed in the IBD clinic were recruited. Data on clinical and demographic characteristics (age, type of IBD, disease behavior (Montreal) and activity (HBI, Mayo score), smoking habits, familial predisposition, current treatment, educational and marital status, current employment) were registered on a dedicated database. All patients agreed to fill in the WPAI (Work Productivity and Activity Impairment) questionnaire and the EQol-5D (European Quality of Life - 5 Dimension) VAS scale. Data of the National Institute of Statistics (ISTAT) on employment rates in Italy were used for comparison.
There were no significant differences between males and females regarding age, educational and marital status and disease characteristics except disease activity rate, which was higher in males. There was a significant difference in the employment status since 58.5 % of women were unemployed versus 34.7% of men (p=0,02). Overall, there were no differences in WPAI scores (absenteeism, presenteism, overall work and regular activities impairment) and EQoL between males and females. In male patients with active disease absenteeism (p=0,04), presenteism (p=0,02) and work productivity impairment (p=0,04) rates were significantly higher as compared to patients in remission, quality of life was not affected, in females with active disease we observed a higher rate of absenteism (p=0,04) and daily regular activities impairment (p=0,04) as well as quality of life (p=0,015).
Gender significantly influences occupational status in IBD, since women are more often unemployed. Work productivity is impaired in both men and women with active disease, but women are more prone to the negative impact of the disease on daily regular activities and quality of life than men. These preliminary Results should be kept in mind in clinical management of IBD female patients.