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P527 Characterization of variables determining satisfaction with life in Crohn's Disease patients

O. Sarid1, V. Slomin-Nevo1, H. Vardi2, D. Schwartz3, A. Fich3, D. Greenberg4, M. Friger2, S. Odes*4

1Ben-Gurion University of the Negev, Social Work, Beer Sheva, Israel, 2Ben-Gurion University of the Negev, Public Health, Beer Sheva, Israel, 3Soroka University Hospital, Gastroenterology, Beer Sheva, Israel, 4Ben-Gurion University of the Negev, Health Systems Management, Beer Sheva, Israel


Satisfaction with Life is a vital personality resource impacting the individual's ability to cope with life stressors including chronic disease. Yet, among Crohn's Disease (CD) patients the protective health-promoting effects of this factor is incompletely understood. Our aim was to assess the associations between Satisfaction with Life in CD patients and clinical and demographic factors, psychological symptoms and family support.


Consecutive patients consenting to participate in an ongoing socio-economic study of CD in the Israeli adult patient population completed the following self-administered socio-psychological questionnaires: Satisfaction with Life Scale (SWLS), Brief Symptom Inventory (BSI, measures psychological stress), Carver's Brief COPE Inventory (COPE, measures coping skills) and MacMaster Family Assessment Device (FAD). Demographics, clinical data, Harvey-Bradshaw Index (HBI) of disease activity and Irvine's SIBDQ were obtained simultaneously.


The cohort comprised 148 men (40.4%) and 219 women (59.6%), mean age ± SD: 35.7 ± 13.4 and 40.3 ± 15.1 years respectively (p < 0.01). There were no significant differences of disease duration (men 10.5 ± 8.8 and women 12.5 ± 9.4 years), Harvey-Bradshaw Index (6.5 ± 5.4 and 6.5 ± 5.6), SIBDQ (48.2 ± 14.8 and 46.6 ± 13.5) and years of education (14.2 ± 3.0 and 14.5 ± 2.7). SWLS mean scores were moderate and similar in men (21.0 ± 7.9) and women (22.8 ± 7.4). FAD mean scores (6 domains) were similar in men (1.80 ± 0.53) and women (1.78 ± 0.58). BSI in all 9 domains indicated low anxiety levels, with mean score in men 0.99 ± 0.94, and women 0.95 ± 0.87. COPE demonstrated that women used significantly more active coping, self-distraction, emotional support, instrumental support and venting than men (all at least p < 0.03), while substance use was greater in men than women (p < 0.01). In a best fit model with R squared = 0.514, the following factors (beta) were found to be significant predictors of Satisfaction with Life: economic status (0.229), COPE positive reframing (0.136), COPE substance use (-0.101), BSI depression (-0.453) and FAD (-0.192). Age at disease onset and HBI were not significant predictors.


Satisfaction with Life in CD patients is determined by the interplay of economic status and a variety of psychological parameters, but not disease severity. These findings show an important role for psychological treatment and family support in the overall management of CD patients.