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* = Presenting author


M. Orofino*1, J.-C. Grimaud2

1Collège Ostéopathique de Provence Aix-Marseille, Research department, Marseille, France, 2Hôpital Nord, Gastroenterology Unit, Marseille, France


Crohn's disease, chronic inflammatory disease characterized by periods of flares and remissions, is very debilitating for patients.

The objective of this study is to evaluate the improvement of the quality of life of patients with Crohn's disease with visceral osteopathic technique, the root of the mesentery.



This study examined 27 patients (18 to 75 years), followed in the hepato-gastroenterology service at North Hospital (Marseille) and randomized into two groups:

- G1: 14 patients in the group receiving visceral osteopathic technique

- G2: 13 in the control group without treatment osteopathic

Patients meet the following inclusion criteria:

- Crohn's Disease diagnosis established by a gastroenterologist

- Crohn's located at the small intestine and / or colon

- Topics stable, in remission, following appropriate treatment

Excluded from the study, subjects with other recognized medical condition, or according to any other treatment.

Material and Methods

This study, single-blind test, has two assessments of the quality of life conducted at three-week intervals (D0 and D21) from IBDQ (Inflammatory Bowel Disease Questionnaire), whose score ranges from 32-224.

At D0, the patient responds to the IBDQ and receives treatment:

- G1: visceral osteopathic technique on the root of the mesentery

- G2: control, "virtual manipulation" (palpation of the small intestine and colon framework without action on the vasculature and innervation)

On D21, the two groups match in the new IBDQ


To evaluate the effect of visceral osteopathic technique on the quality of life of patients, we perform a paired t-Student test.

G2 control group shows no variation in the evolution of the IBDQ (p = 0.22). However, the score of the patients in group treated with osteopathy G1 increased significantly between D0 and D21 (p <0.001), indicating a significant improvement in their quality of life.


Visceral osteopathic technique on the root of the mesentery significantly improves the quality of life of patients with Crohn's disease.

As an osteopath, we can not limit ourselves to a single technique in our treatment. A full osteopathic care would reduce other symptoms of Crohn's disease, such as bone and joint pain, and further improve the quality of life of patients.