P654 Relationship between use of complementary and alternative medicine (CAM) and health related quality of life (HRQoL) among patients with inflammatory bowel disease (IBD).
R. Opheim*1, M. Lie Høivik1, T. Bernklev2, L.-P. Jelsness-Jørgensen3, 4, B. Moum1
1Oslo University Hospital, Department of Gastroenterology, Oslo, Norway, 2Telemark Hospital Trust, Research and Development Department, Skien, Norway, 3Østfold Hospital Trust, Department of Gastroenterology, Fredrikstad, Norway, 4Østfold University College, Faculty of Health and Social Studies, Fredrikstad, Norway
Use of complementary and alternative medicine (CAM) has been reported to be frequent among patients with inflammatory bowel disease (IBD). Patients report improvement of health-related quality of life (HRQoL) and well- being as one of the important reasons of CAM use. Few studies however, have assessed the potential association between CAM use and HRQoL in IBD. The aim of this study was to investigate associations between CAM use and HRQoL in IBD patients.
From 2011 to 2012 adult IBD outpatients from 14 hospitals in Norway were included. CAM use was assessed with the International-CAM-Questionnaire and HRQoL with the Short Form-36 (SF-36). In addition, socio-demographic and clinical data was collected, including the Harvey-Bradshaw Activity Index (HBI) in Crohn's disease (CD) and the Simple Clinical Colitis Activity Index (SCCAI) in ulcerative colitis (UC). Univariate analysis of variance (ANCOVA) was used to assess the association between CAM use and HRQoL, controlling for age, gender, educational level and disease activity.
Two hundred and ninety-nine patients with an established IBD diagnosis completed the questionnaires, out of which 235 (78.6%) had evaluable questionnaires (UC n=106, 41% females, and CD n=129, 56% females). A higher proportion of the UC patients (52%) compared with CD patients (38%) used CAM, p=0.003. The SF-36 scores were significantly lower in CD patients compared to UC patients in 3 out of 8 dimensions. In UC, patients with disease activity (SCCAI score ≥ 3) had significantly lower SF-36 scores in 5 out of eight dimensions. In CD, patients with disease activity (HBI score ≥ 4) had significantly lower SF-36 scores in all dimensions. Furthermore, after controlling for gender, age, educational level and disease activity, the UC CAM users had significantly lower SF-36 scores in all dimensions, except from physical function, compared with patients not using CAM. In CD, no differences in SF-36 scores were found between CAM users and non-users.
UC patients using CAM reported lower SF-36 scores compared to non-users. Among CD patients, no difference between CAM users and non-users in SF-36 scores was found. The relationship between CAM use and HRQoL needs further investigation.
- Posted in: Poster presentations: Epidemiology (2015)