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* = Presenting author

P129 Factors associated with anxiety and depression in Korean inflammatory bowel disease patients

S.-K. Park*, Y. S. Jung, D. I. Park

Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea

Background

Psychological distress is highly prevalent in patients with inflammatory bowel disease (IBD). However, most studies on this topic have been conducted exclusively in Western countries. The aim of this study was to evaluate the disease characteristics and socioeconomic factors associated with anxiety and depression in Korean patients with IBD in the remission state.

Methods

From July 2013 to December 2013, 142 patients with IBD who were regularly evaluated at a single tertiary academic medical Centre completed self-report questionnaires, including the Hospital Anxiety and Depression Scores, Modified Morisky Adherence Scale-8, socioeconomic deprivation score, and the Crohn’s and Colitis Knowledge Score questionnaires.

Results

In total, 142 IBD patients (67 with Crohn’s disease [CD], 75 with ulcerative colitis [UC]) were enrolled. In the CD group, 30 patients (44%) were anxious and 10 patients (15%) were depressed, and in the UC group, 31 patients (41%) were anxious and 18 patients (24%) were depressed. Using multivariate analysis on data from the CD patients, the factor found to be associated with anxiety was socioeconomic deprivation (odds ratio [OR] 3.95, 95% CI 1.14–13.67, p = 0.030], and the factors associated with depression were disease duration (OR 1.24, 95% CI 1.01–1.53, p = 0.040) and socioeconomic deprivation (OR 8.22, 95% CI 1.57-43.03, p = 0.013). In the UC group, there was no significant independent predictor of anxiety and/or depression; however, low income tended to be associated with depression (OR 2.78, 95% CI 0.83–9.32, p = 0.096).

Conclusion

Despite clinical remission, a significant number of IBD patients present with anxiety and/or depressive symptoms. IBD patients in remission, particularly those that are especially deprived, should be provided with appropriate psychological support.