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* = Presenting author

P241 Risk factors associated with perianal Crohn’s disease in Korean children

E. Ryoo*, K. Lim, H. Tchah

Gachon University, Gil Hospital, Paediatrics, Incheon, South Korea

Background

According to the increasing incidence of paediatric Crohn’s disease (PCD) in Korea, several reports about focusing on the incidences and treatment are published. However, one of the relatively rare complications, perianal lesions is not well known. Therefore, we investigated the incidence and the risk factors of perianal Crohn’s disease in Korean children.

Methods

We retrospectively reviewed medical records in children (age ≤ 18 years) who confirmed with Crohn’s disease in Gachon University Gil Hospital between 2000 and 2014. After dividing into 2 groups according to the perianal lesions, we identified the risk factors of the PCD with logistic regression analysis.

Results

Of 69 children, mean age was 15.4 ± 2.2year, 51 (73.9%) were male, and 54 (78.3%) had perianal PCD. Gender, BMI, age at initial diagnosis, chief complaints, and other associated symptoms and signs were not significantly different between the 2 groups, but mean duration of symptoms was more longer in perianal PCD (p = 0.007). Of laboratory findings, Hb was lower and Hct was higher in perianal PCD (OR = 0.05; 95% CI 0.00–0.82; p = 0.04, OR = 2.98; 95% CI 1.06–8.35; p = 0.04). Penetrating lesions were more predominant in perianal PCD (p = 0.049). Paris classification was not different between the 2 groups.

Conclusion

The relatively higher incidence and longer symptom duration in Korean children with PCD suggest the delayed diagnosis. Therefore, clinical suspicion about Crohn’s disease is needed in children with perianal lesions.