P363 The impact of transition to adult gastroenterology services on health-related quality of life in young adult patients with IBD: the UK TRANSIT study
McCartney S.*1, Lindsay J.2, Russell R.3, Gaya D.3, Shaw I.4, Murray C.5, Finney-Hayward T.6, Sebastian S.7
1University College London Hospitals NHS Foundation Trust, London, United Kingdom 2Barts Health NHS Trust, London, United Kingdom 3NHS Greater Glasgow and Clyde, Glasgow, United Kingdom 4Gloucestershire Hospitals NHS Foundation Trust, Gloucester, United Kingdom 5Royal Free London NHS Foundation Trust, London, United Kingdom 6AbbVie, Maidenhead, United Kingdom 7Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom
Paediatric patients with IBD move from family-oriented paediatric to individual-oriented adult gastroenterology services at a time of significant physical and psychological change. There is some evidence that coordinated transition programmes may improve outcomes in IBD when transferring to adult services. The health-related quality of life (HRQoL) of adolescent/young adults following transfer to adult services has not been described.
An observational, multi-centre, mixed methodology study of adolescent/young adult patients (age ≥16 years) with a confirmed diagnosis of IBD before age 16 who had been under the care of adult services for ≥12 months at recruitment was conducted in 11 UK centres. Transition visits were defined as those involving clinical staff from both paediatric and adult services; transition patients had attended ≥2 transition visits and non-transition patients attended none. Patients completed the following questionnaires at recruitment: Short Inflammatory Bowel Disease Questionnaire (SIBDQ), Inflammatory Bowel Disease Control Questionnaire (IBDCQ-8 and IBDCQ-VAS [visual analogue scale]), Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Index (WPAI) and self-reported days of education lost due to IBD. Socioeconomic status was measured using the English Index of Multiple Deprivation (IMD).
Transition (n=95) and non-transition (n=34) patients were similar in terms of demographic and clinical characteristics at recruitment (transition: median age 19.6 years; 47% female; 78% CD; median 2.1 years since index visit) and non-transition patients (n=34; median age 19.3 years; 41% female; 74% CD; median 2.3 years since index visit; all p>0.05). Overall, patient-reported quality of life and perceived IBD control were similar in transition and non-transition patients (all p>0.05; see table). Significant symptoms of anxiety and depression were reported by 20% and 2%, respectively, of transition patients and by 13% and 0%, respectively, of non-transition patients (p>0.05; see table). Of those in employment, 16% of transition and 27% of non-transition patients had time off work in the previous week. Time lost from education and socioeconomic status were similar in transition and non-transition patients (both p>0.05; see table).
Surveys collected from at least 120 adolescent/young adult patients with IBD taking part in this study describe health related quality of life at this time point.