P122 Longitudinal follow-up of body mass index as a predictor for severe disease course in children with inflammatory bowel disease
A. Yerushalmy-Feler*1,2, S. Cohen1,2
1Tel Aviv Sourasky Medical Center, Pediatric Gastroenterology, Tel Aviv, Israel, 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Recent studies have shown that obesity may be associated with severe disease course in inflammatory bowel disease (IBD). The aims of this study were to present the longitudinal course of height, weight and body mass index (BMI) in children with IBD and to describe the impact of BMI on the clinical course of the disease.
We reviewed the medical records of children with IBD from the database of the 'Dana-Dwek' Children's Hospital between June 2010 and August 2018. Anthropometric data were longitudinally collected every 6 months as were disease characteristics, course and therapy. Patients were categorised in quartiles according to BMI percentile.
Of 152 children, 85 had Crohn's disease (CD) and 67 had ulcerative colitis (UC). The median age (IQR) at diagnosis was 14 (12–15.5) years. During a median (IQR) follow-up of 2.95 (1.73–4.5) years, height Z-scores in the study population have not significantly changed. Weight and BMI Z-scores increased in the first 18 months since diagnosis in CD (
BMI in the lower and upper quartiles in 18 months since diagnosis was associated with more severe disease course in children with IBD. The results support using BMI as a predictor of IBD course and prognosis.