P154 Development of a novel ultrasound based score for assessing disease activity in ulcerative colitis: preliminary results
P. Kakkadasam Ramaswamy*1, A. Yelsangikar1, K. V. Nagarajan1, A. Nagar1, N. Bhat1
1Aster CMI Hospital, Department of Gastroenterology, Liver Diseases and Clinical Nutrition, Bangalore, India
Colonoscopy based scores are the gold standard for assessing disease activity in ulcerative colitis (UC). The aim of this study was to develop a new bowel ultrasound (USG) based score for assessing disease activity in UC and to assess its correlation with Mayo endoscopic score (MES).
Patients who underwent colonoscopy for assessment of disease activity also underwent USG within 2 weeks. Endoscopic activity was graded with MES; clinical disease activity was assessed using the Total Mayo Score (TMS). All assessments were performed for the rectum, sigmoid, descending, transverse, and ascending colon and caecum. A novel score based on Colonic wall thickness (CWT), loss of bowel wall stratification, Doppler activity (D) was calculated for each segment and correlated to the MES.
USG based score.
A total of 102 colonic segments were analysed. Median CWT was lower in patients with MES 0-1 when compared with MES 2-3 (3 mm vs. 4.1 mm,
The novel ultrasound score has excellent correlation with MES. USS assessment of the sigmoid colon correlates with overall endoscopic activity and the Total Mayo score.