P192 Prevalence and factors associated with impaired food-related quality of life: a cross-sectional survey of 1223 people with inflammatory bowel disease
W. Czuber-Dochan1,2, T. Murrells2, M. Morgan3, M. Lomer4, J. O. Lyndsay5,6, K. Whelan7
1King's College London, Faculty of Life Sciences and Medicine, Department of Nutritional Sciences, London, UK, 2King's College London, Faculty of Nursing, Midwifery and Palliative Care, London, UK, 3King's College London, Institute of Pharmacological Sciences, London, UK, 4King's College London, Department of Nutritional Sciences, London, UK, 5Queen Mary University of London, Blizard Institute, Barts and the London School of Medicine, London, UK, 6Barts Health NHS Trust, The Royal London Hospital, London, UK, 7King's College Londom, Faculty of Life Sciences and Medicine, School of Life Course Sciences, London, UK
Inflammatory bowel disease (IBD) patients often report that dietary intake and the enjoyment of food is affected by their condition. However, the prevalence of impaired food-related quality of life (FR-QoL) and associated factors have not been previously explored. This study aimed to determine the levels of FR-QoL and factors associated with it in a large, nationally representative sample of people with IBD.
A convenience sample of 1576 IBD outpatients ≥16 years old were recruited from seven UK centres. Patients consuming the majority of their intake as food completed previously validated questionnaires to capture demographic data, FRQoL-29, quality of life (IBDQ UK), IBD-distress (IBD-DS), IBD-fatigue (IBD-F), and anxiety and depression (HADS). A health professional recorded disease activity (HBI, SCCAI), disease classification (Montreal), blood results, body mass index and malnutrition risk (MUST). FR-QoL was regressed onto the explanatory variables (univariable/multivariable) using the Stata MI (20 imputed datasets) procedure.
Data from 1223 patients were available (78% response, 65% CD and 51% female). FR-QoL mean score was 80.1 [SD 26.9] (minimum 29, maximum 145, higher score = better FR-QoL), considerably lower in comparison to previously measured healthy volunteers [123.0, SD 16.5]. The four items rated as the most severe (Strongly agree/Agree) were ‘avoiding food and drink I know does not agree with my IBD’ (71%), ‘being more aware of what I am eating due to my IBD’ (70%), ‘certain foods have triggered symptoms of my IBD’ (69%) and ‘enjoyment of a particular food or drink has been affected by the knowledge that it might trigger my IBD symptoms’ (67%). Twenty-six factors (demographic, clinical, drug-related, psycho-social) were significantly associated with impaired FR-QOL in univariate analysis. However, in the multi-variable regression, only lower educational level (
In this first large study reporting FR-QoL in IBD, many factors were identified as having a significant negative effect on patients with IBD. Understanding the relationship between IBD and FR-QoL may improve communication between health professionals and patients regarding its impact.