P236 Inflammatory bowel disease epidemiology a tertiary centre in Brazil
R. S. Parra*1, M. R. Feitosa1, S. C. Ferreira2, B. E. Caetano1, A. FavorettoJr1, J. J. Ribeiro da Rocha1, O. Féres1, L. E. d. A. Troncon2
1Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil, Surgery and Anatomy, Ribeirão Preto, SP, Brazil, 2Ribeirão Preto Medical School, University of São Paulo, Division of Gastroenterology, Department of Medicine, Ribeirão Preto - SP, Brazil
Data regarding the prevalence of inflammatory bowel disease (IBD) are scarce in Brazil. The aim of this study was to determine the prevalence of IBD and to analyse the demographical, clinical phenotipes of these cases in a tertiary IBD Unity in Southeast Brazil.
Retrospective analysis from the adult population‐based IBD cohort of Clinical Hospital of Ribeirão Preto Medical School, University of São Paulo, Brazil, between 2014 and 2018. Medical records consisted in age, gender, occupation, disease (Crohn’s disease [CD]; ulcerative colitis [UC]), disease location, moderate-to-severe feature, previous surgeries, treatments, and biological therapy.
Of 579 patients, 325 had CD and 254 had UC. Fifty-three (53%) were females. Mean age at diagnosis was 32.4 years. Eighty-two per cent of patients were moderate to severe. The mean time of disease was 159 months (13.25 years). Two hundred and two patients (
|Variable||CD (||UC (|
|Female||154 (47.4%)||154 (60.6%)*|
|Age at diagnosis (years)||30.4||34.81|
|Disease duration (months)||166.5||149.7|
|Biological therapy||208 (64%)*||66 (26%)|
|Previous surgeries||192 (59.1%)*||50 (19.7%)|
|Cancer||5 (1.54%)||2 (0.79%)|
|Cholangitis||7 (2.2%)||11 (4.3%)|
|Deaths||9 (2.8%)||0 (0%)|
|Employed||195 (47.4%)||129 (50.8%)|
Clinical features in UC and CD. *Statistical significantly.
There was a predominance of patients with CD in our IBD Unit. Most of UC patients were female. CD was associated with higher risk of surgery, biological therapy and death.1,2
1. Lima Martins A, Volpato RA, Zago-Gomes MDP. The prevalence and phenotype in Brazilian patients with inflammatory bowel disease.
2. Gasparini R, Sassakji LY, Saad-Hossne R. Inflammatory bowel disease epidemiology in São Paulo State, Brazil.