P242 Accuracy of Doppler transabdominal ultrasound in assessing disease severity and extent in IBD
S. Sagami*1, T. Kobayashi1, T. Kanazawa2, K. Aihara2, H. Morikubo1,3, R. Ozaki1,3, S. Okabayashi1, M. Matsubayashi1,3, A. Fuchigami1,3, H. Kiyohara1,3, M. Nakano1,3, T. Hibi1
1Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan, 2Kitasato University Kitasato Institute Hospital, Department of Clinical Laboratory, Tokyo, Japan, 3Kitasato University Kitasato Institute Hospital, Department of Gastroenterology and Hepatology, Tokyo, Japan
A paradigm shift in the treatment of inflammatory bowel disease (IBD) has emerged with recent medical advancements. Beyond clinical remission, endoscopic mucosal healing has become a major therapeutic goal of IBD and is associated with better long-term prognosis. Therefore, endoscopic evaluation is considered indispensable, however, frequent ileocolonoscopy (CS) may not be feasible due to its invasiveness. Transabdominal ultrasonography (TAUS) is a non-invasive imaging technique which enables to frequently monitor the disease and its utility has been previously reported. This study examined the usefulness of Doppler TAUS in assessing disease severity of IBD comparing with CS for each ileocolonic segment.
A retrospective chart review of 60 patients with IBD (ulcerative colitis (UC) 35, Crohn’s disease (CD) 25) who were examined both CS and Doppler TAUS from May 2017 to November 2018 within the interval of 1 month was conducted. The Mayo Endoscopic Subscore (MES) or the Simple Endoscopic Score for Crohn's disease (SES-CD) were used for CS and Limberg score was graded from Grade 0 to 4 for Doppler TAUS  . Endoscopic scoring indices (MES, SES-CD) and Limberg score were compared per-segment (ileum, ascending, transverse, descending, sigmoid and rectum) and per-patient. The sum of each score was calculated. Finally, the association of Limberg score with endoscopic indices was assessed by non-parametric Spearman rank correlation (
Limberg score was significantly associated with MES (rs = 0.68,
Table 1. Correlation (
Doppler TAUS is a useful monitoring tool alternative to CS, however, is less accurate in the assessment of rectum.
1. Sturm A, Maaser C, Calabrese E,
2. Limberg B. Diagnosis of chronic inflammatory bowel diseases by ultrasonography.