P304 Predicting severity in Crohn's disease
C. Gouveia*1, C. Gomes1, L. Glória1, J. Torres1, M. Cravo2
1Hospital Beatriz Ângelo, Gastroenterology, Lisbon, Portugal, 2Hospital Beatriz Ângelo, Gastroenterology, Lisboa, Portugal
Stratification of patients with Crohn's disease (CD) according to the risk of developing complications is essential to delineate therapeutic approach. A recent score (Siegel
Retrospective study, including incident patients with CD at our hospital between January 2012 and July 2017. The score was calculated at dx and at the end of follow-up, and information about disease course was collected.
In total, 64 patients (32 women), with mean age at dx 33.4 ± 15.4 years. At dx 29 patients (45%) had L1 disease, 12 patients L2, 22 patients L3, and 1 patient L4. Forty-three patients (67%) had B1 phenotype, 7 patients B2, and 14 patients B3. At follow-up, 28 patients (44%) required surgery, 33 (52%) required hospitalisation, and 2 had phenotype progression. Median score at dx was 16 (4–50) and at follow-up was 9 (0–39). At dx score was higher in younger patients (22 A1 vs. 14 A3,
The aforementioned severity score seems to be a promising instrument for stratification and prognosis of patients with CD, and its usefulness should be validated in prospective studies.