P812 Anaemia during Crohn's disease: Does its mechanism predict the extent of the disease?
A. Sabbek*1, N. Elleuch2, M. Ksiaa2, E. Hammami2, H. Jaziri2, A. Braham2, S. Ajmi2, A. Ben Slama2, A. Jmaa2
1Sahloul Sousse, Gastroenterology, Sousse, Tunisia, 2Sahloul Sousse, Sousse, Tunisia
Anaemia is the most common extraintestinal complication during Crohn's disease (CD). Several studies have looked at possible mechanisms and its treatment but few have tried to link it to a specific localisation of the disease. The aim of our study is to determine the prevalence, mechanisms of anaemia during CD and seek for a locational value by type.
A retrospective descriptive and analytical study, spread out over 5 years, including patients diagnosed with a CD at the department of gastroenterology of Sousse. Anaemia was defined as haemoglobin < 13 g/dl in men and < 12 g/dl in women.
We collected 166 patients of mean age 42.9 years [15–73 years] and sex ratio 0.55. Two thirds of the patients were anaemic (75.3%) with an average haemoglobin level of 10.4 g / dl [6.7–11.8 g/dl]. Iron deficiency anaemia was found in 62.4% of cases (
In our study, anaemia was predominantly iron-deficient and was associated with ileocolic localisation, unlike inflammatory anaemia, which had no locating value. More large studies are needed to confirm our hypotheses.