Horizon 2020 - BIOCYCLE Project:

bio-cycle-iconBIOlogical therapy CYCLEs towards tailored, needs-driven, safer and cost-effective  management of Crohn’s Disease




  • Congress special: Call for similar cases – ECCO CONFER Round 2
  • BIOCYCLE Research Project selected for EU Horizon 2020 funding
  • This project receives funding from the "European Union’s Horizon 2020 research and innovation programme" under grant agreement No 633168 — BIOCYCLE (PHC-13-2014).
  • Focus on treatment de-escalation in patients with Crohn’s Disease in sustained steroid-free remission under combination therapy with infliximab and immunosuppressant.
  • Looking at cost and safety issues  
  • A three-arm controlled trial comparing combination maintenance with infliximab withdrawal or with immunosuppressant withdrawal. 
  • Beside clinical efficacy end-points, the project is aiming to assess biomarker prediction, cost- effectiveness, and the perceptions of patients/health care providers/health authorities.
  • Project implementation within supporting networks of BSG, CED, SOIBD and ECCO.GETAID

 pdfBIOCYCLE Poster