P135 Disease-related worries and concerns in UK patients with ulcerative colitis: 2-year data from ICONIC
N. Bhala1, A. Hart2, D. Watts3, S. Lewis4, S. Ghosh5, S. van Haaren6, C. Hansell6, T. Ahmad7
1Queen Elizabeth Hospital Birmingham, Gastroenterology, Birmingham, UK, 2St Mark’s Hospital, IBD Unit, Harrow, UK, 3NHS Forth Valley, Gastroenterology, Stirling, UK, 4Plymouth Hospitals NHS Trust, Gastroenterology, Plymouth, UK, 5University Hospitals Birmingham NHS Foundation Trust, Gastroenterology, Birmingham, UK, 6AbbVie Ltd., Medical, Maidenhead, UK, 7Royal Devon and Exeter Hospital, Gastroenterology, Exeter, UK
ICONIC is the largest ongoing, prospective, multi-country observational study assessing cumulative disease-associated burden in adults with ulcerative colitis (UC) under routine care. This local subanalysis evaluated patient worries and concerns up to 2 years in UK patients using the Rating Form of inflammatory bowel disease (IBD) Patient Concerns (RFIPC) questionnaire.
Adults with early UC (diagnosed ≤36 months) were enrolled irrespective of treatment regimen or disease severity. Patients completed RFIPC, a 25-item questionnaire comprising frequently reported worries/concerns of IBD patients, at each visit (6-month intervals). Responses are scored on a 10-cm visual analogue scale for each individual question from 0 (no concerns) to 10 (a great deal). The mean of all 25 items represents the total score (lower scores indicate less worries/concerns). In this analysis, data are reported for UK patients as observed using descriptive statistics at baseline (BL, visit 1 [V1]), 1 year (V3), and 2 years (V5). Patients were stratified by physician-assessed disease severity (mild, moderate, severe, in remission) at baseline.
Sixty-three UK patients were included (37 [59%] female; mean ± SD age 43.4 ± 15.7 years; median [interquartile range] time since UC diagnosis 126 (59 to 260) days; physician-assessed UC severity: mild 18 [29%], moderate 18 [29%], severe 11 [17%], in remission 16 [25%]). Mean ± SD total RFIPC scores for all patients were 2.9 ± 2.3 (
Despite all UK centres having MDTs and most having a psychologist