P162 Earlier (luminal) surgery is associated to reduced postoperative morbidity in ileocaecal Crohn’s disease: results from SURGICROHN – LATAM study.
IBD Latam Consortium, S.(1);Avellaneda, N.L.(2);Saddy Rodrigues Coy, C.(3);Sarubbi Fillmann , H.(4);Saad-Hossne , R.(5);Muñoz, J.P.(6);García-Duperly , R.(7);Bellolio, F.(8);Rotholtz, N.(9);Rossi, G.(10);Marquez V, J.R.(11);Cillo, M.(12);Lacerda-Filho, A.(13);Carrie, A.(2);Yuki Maruyama , B.(14);Sarubbi Fillmann , L.(4);Ferro, E.(6);Londoño-Schimmer , E.(15);Iglesias, A.(8);Bras Harriott, C.(9);Campana, J.P.(10);Londoño Estrada, D.(16);Kotze, P.G.(17)*;
(1)Latam Colab, Colorectal Surgery, Buenos Aires, Argentina;(2)CEMIC University Hospital, Colorectal Surgery, Buenos Aires, Argentina;(3)Campinas State University UNICAMP, Colorectal Surgery, Campinas, Brazil;(4)Pontificia Universidad Católica de Rio Grande do Sul, Colorectal Surgery, Porto Alegre, Brazil;(5)Paulista State University UNSEP, Colorectal Surgery, Sao Paulo, Brazil;(6)Nueva Proctologia, Colorectal Surgery, Buenos Aires, Argentina;(7)Fundación Santa Fé de Bogotá, Colorectal Surgery, Bogota, Colombia;(8)Pontíficia Universidad Católica de Chile, Colorectal Surgery, Santiago, Chile;(9)Hospital Aleman de Buenos Aires, Colorectal Surgery, Buenos Aires, Argentina;(10)Hospital Italiano de Buenos Aires, Colorectal Surgery, Buenos Aires, Argentina;(11)Clinica Las Americas, Colorectal Surgery, Medellin, Colombia;(12)Hospital Británico, Colorectal Surgery, Buenos Aires, Argentina;(13)Hospital Felicio Rocco, Colorectal Surgery, Belo Horizonte, Brazil;(14)Pontificia Universidade Católica do Paraná PUCPR, Colorectal Surgery, Curitiba, Brazil;(15)Fundacion Santa Fe, Colorectal Surgery, Bogota, Colombia;(16)Hospital Felicio Rocho, Colorectal Surgery, Belo Horizonte, Brazil;(17)Pontificia Universidad Catolica de Parana, Colorectal Surgery, Curitiba, Brazil; SURGICAL IBD LATAM CONSORTIUM
Background
Background: Early surgical resection is an emerging concept for patients with ileocaecal Crohn’s disease (CD). The aim of this study was to compare postoperative outcomes after ileocaecal resections between patients with luminal and complicated CD.
Methods
Methods: A retrospective analysis of patients operated for ileocaecal CD during an 8-year period in ten tertiary referral academic centres from Latin America was performed. Patients were allocated into 2 groups: those operated for early (luminal) disease (Early Crohn’s Disease -ECD-) and for complications of CD (Complicated Crohn’s disease -CCD-). A comparative analysis was performed regarding short-term outcomes of surgery, considering overall postoperative complications as main outcome.
Results
Results: 337 patients were included in the analysis, 60 (17.80%) in the ECD group. Smoking and exposure to perioperative biologic drugs were more prevalent in CCD group. CCD patients had increased requirement of urgent surgery (26.71 vs. 15%, p=0.056), longer operative time (164.25 vs. 90.53 minutes, p< 0.01), lower rates of primary anastomosis (90.23 vs. 100%, p=0.012), increased rate of overall postoperative complications (33.21 vs. 16.67%, p=0.013), more reoperations (13.36 vs. 3.33%, p=0.026), and higher rates of major anastomotic fistulas and hospital stay. On multivariable analysis, smoking (p= 0.001,95%CI: 2.59-32.11), operative time (p=0.022,95%CI:1-1.02), associated procedures (p=0.036,95%CI:1.09-15.72) and intraoperative complications (p=0.021,95%CI:1.45-92.31) were independently related to presenting postoperative complications.
Conclusion
Conclusion: Early (luminal) ileocaecal resections were associated to lower rates of overall postoperative complications. Proper timing for surgery, avoiding delays in surgical indication can impact postoperative outcomes.