P294 Clinic features and the prognosis of colonic Crohn’s disease
D. Ozgur1, A.I. Hatemi2, Y. Erzin2, A. Çelik2
1Department of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey, 2Department of Gastroenterology, Istanbul University-Cerrahpasa, Istanbul, Turkey
In this study, we aimed to investigate the prognosis of colonic Crohn’s disease (CD) and to compare colonic CD with ileocolonic CD.
This study included 63 patients with colonic CD who were followed at least 1 year. The same number of patients with ileocolonic CD whose age of diagnosis and sex were similar to colonic CD patients were included in the study. Data about demographics, serological, clinic characteristics, medical treatment, surgical treatment requirements and complications during follow-up were obtained retrospectively from patient files.
The files of 1289 CD patients who were followed up at a clinic of inflammatory bowel disease of Cerrahpaşa School of Medicine were scanned. There were 63 patients with colonic CD. Control group was formed as it was noted in the Methods section. The rate of patients who smoked was lower in colonic CD (47.6% vs. 65%,
The results of our study showed that colonic CD has different phenotype characteristics, treatment response and laboratory features than ileocolonic Crohn’s disease. Colonic CD has a lower penetrating and/or stenosing phenotype rate than ileocolonic CD. Surgery and hospitalisation were less common in patients with colonic Crohn’s disease. In addition, patients with colonic CD have a higher endoscopic remission rate. For these reasons, we conclude that colonic Crohn’s disease has a better prognosis than ileocolonic Crohn’s disease.