DOP Session 9

  • 17:20-18:20 Digital Oral Presentation Session 9 - Advances in IBD Pathophysiology
    Room: Strauss 1-2, Ground Floor, Congress Centre
    Chairs:
     TBC
    Jesús Rivera-Nieves, San Diego, United States
      17:20-17:26 DOP073: Results of the sixth ECCO Scientific Workshop: The pathogenesis of inflammatory extraintestinal manifestations of Inflammatory Bowel Disease - implications for research, diagnosis and therapy
    C.R.H. Hedin1, S.R. Vavricka2, A.J. Stagg3, A. Schoepfer4, T. Raine5, L. Puig6, U. Pleyer7, A. Navarini8, A.E. van der Meulen – de Jong9, J. Maul10, K.H. Katsanos11, A. Kagramanova12, T. Greuter13, 14, Y. Gonzalez Lama15, F.A. van Gaalen16, P. Ellul17, J. Burisch18, D. Bettenworth19, M. Becker20, G. Bamias21, F. Rieder22
    1. Karolinska University Hospital, Gastroenterology unit, Patient Area Gastroenterology, Dermatovenereology and Rheumatology, Stockholm, Sweden
    2. Centre for Gastroenterology and Hepatology, Zurich, Switzerland
    3. Barts and The London, Queen Mary's School of Medicine and Dentistry, Centre for Immunobiology, London, United Kingdom
    4. CHUV - Centre Hospitalier Universitaire Vaudois, Department of Gastroenterology, Lausanne, Switzerland
    5. University of Cambridge, Department of Medicine, Cambridge, United Kingdom
    6. Universitat Autònoma de Barcelona, Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    7. Charite - University Hospital Berlin, University Eye Clinic, Uveitis Center, Berlin, Germany
    8. University Hospital Zurich, Department of Dermatology, Zurich, Switzerland
    9. Leiden University Medical Center (LUMC), Department of Gastroenterology and Hepatology, Leiden, Netherlands
    10. Gastroenterologie am Bayerischen Platz, Berlin, Germany
    11. University and Medical School of Ioannina, Department of Internal Medicine I, Division of Gastroenterology and Hepatology, Ioannina, Greece
    12. The Loginov Moscow Clinical Scientific Centre, IBD Department, Moscow, Russian Federation
    13. Mayo Clinic, Gastroenterology Research Unit, Rochester, MN, United States
    14. University of Zurich, Department of Gastroenterology and Hepatology, USZ, Zurich, Switzerland
    15. Hospital Universitario Puerta De Hierro, Intestinal Inflammatory Disease Unit / IBD Unit, Gastroenterology and Hepatology Service / Gastroenterology and Hepatology Department, Madrid, Spain
    16. Leiden University Medical Center (LUMC), Department of Rheumatology, Leiden, Netherlands
    17. Mater Dei Hospital, Department of Medicine, Division of Gastroenterology, Triq Dun Karm, L-Imsida, Malta
    18. North Zealand University Hospital, Department of Gastroenterology and Hepatology, Frederikssund, Denmark
    19. University Hospital Münster, Department of Medicine B, Gastroenterology and Hepatology, Münster, Germany
    20. Triemli Hospital, Department of Ophthalmology, Zurich, Switzerland
    21. Sotiria Hospital, National and Kapodistrian University of Athens, GI Unit, 3rd Academic Dpt. Of Internal Medicine, Athens, Greece
    22. Cleveland Clinic Foundation, Department of Gastroenterology and Hepatology, Cleveland, United States
      17:26-17:32 DOP074: IL-33 promotes gut mucosal wound healing by inducing miRNA-320 to stimulate epithelial restitution and repair
    L.R. Lopetuso1, 2, C. De Salvo2, L. Di Martino2, N. Rana2, W. Goodman2, F. Scaldaferri1, A. Armuzzi1, A. Gasbarrini1, T.T. Pizarro2
    1. Catholic University of Sacred Heart, Internal Medicine Department, Gastroenterology Division, Rome, Italy
    2. Case Western Reserve University, Pathology, Cleveland, United States
      17:32-17:38 DOP075: Colonic gamma delta t-cells respond innately to NKG2D ligands and are grossly dysregulated in active Inflammatory Bowel Disease
    R.J. Dart1, 2, 3 , P. Vantourout1, 2, A. Laing1, 2, J. Digby-Bell3, N. Powell3, 4, P. Irving3, A. Hayday1, 2
    1. Francis Crick Institute, Immunosurveillance Lab, London, United Kingdom
    2. King's College London, DIIID, London, United Kingdom
    3. Guy's and St Thomas Foundation Trust, Department of Gastroenterology, London, United Kingdom
    4. King's College London, DTIMB, London, United Kingdom
      17:38-17:44 DOP076: IL-3 drives IL-10-secreting Tr1 cells to counteract experimental colitis
    S. Zundler, M. Spocinska, V. Popp, E. Becker, R. Atreya, C. Neufert, I. Atreya, B. Weigmann, M.F. Neurath
    University of Erlangen-Nuremberg, Department of Medicine I, Erlangen, Germany
      17:44-17:50 DOP077: Deep Immunophenotyping reveals a role for Mucosal Associated Invariant T (MAIT) cells in the response to anti-TNF treatment in Crohn’s Disease
    M. Walshe, L.A. Elliott, D. Danso-Abeam, G. Cullen, J. Sheridan, H. Mulcahy, E. Ryan, G. Doherty
    Centre for Colorectal Disease, St. Vincent's University Hospital, Univsersity College Dublin, Dublin, Ireland
      17:50-17:56 DOP078: Visceral and subcutaneous adipose tissues of Crohn’s Disease patients contains bacteria
    C. Serena1, M. Terrón-Puig1, E. Maymó-Masip1, M. Queipo-Ortuño2, J. Sabadell-Basallote1, M.M. Rodríguez1, C. Nuñez-Roa1, M. Menacho3, E. Espin4, A. Zorzano5, M. Millan6, S. Fernández-Veledo1, J. Vendrell1
    1. Hospital Universitari de Tarragona Joan XXIII. Institut d´Investigació Sanitària Pere Virgili (IISPV). Universitat Rovira i Virgili, Tarragona, Spain. CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain, Tarragona, Spain
    2. Servicio de Endocrinología y Nutrición, Campus Teatinos s/n, Hospital Clínico Universitario Virgen de la Victoria, 29010, Málaga, Spain. CIBEROBN, Instituto de Salud Carlos III, Madrid, Spain., Málaga, Spain
    3. Hospital Joan XIII, Digestive Unit, Tarragona, Spain
    4. Colorectal Surgery Unit, General Surgery Service, Hospital Vall d’Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain, Barcelona, Spain
    5. Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain. CIBER de Diabetes y Enfermedades Metabolicas Asociadas, Barcelona, Spain. Departamento de Bioquimica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    6. Hospital Joan XIII, Colorectal Surgery Unit, Tarragona, Spain
       17:56-18:02 DOP079: Heat shock protein GP96 is essential for self-renewal of the intestinal epithelial barrier
    M. Schwarzfischer1, Y. Morsy1, K. Atrott1, C. Stanzel1, S. Lang1, G. Rogler1, 2, M. Scharl1, M. Spalinger1
    1. University Hospital Zurich, Division of Gastroenterology and Hepatology, Zurich, Switzerland
    2. University Hospital Zurich, Zurich, Switzerland
      18:02-18:08 DOP080: Endoplasmic reticulum stress in bordering epithelium of Crohn’s Disease patients with intestinal fibrosis
    S. Hu1, N. Bletard2, C. Massot1, 3, N. Pierre1, F. Quesada Calvo1, G. Paulissen1, N. Smargiasso4, G. Mazzucchelli4, D. Baiwir5, E. De Pauw4, P. Delvenne2, M.-A. Meuwis1, 3, E. Louis1, 3
    1. GIGA-R, Uliege, Translational Gastroenterology, Liège, Belgium
    2. CHU de Liège, Pathological anatomy, Liège, Belgium
    3. CHU de Liège, Hepato-gastroenterology and digestive oncology, Liège, Belgium
    4. Uliege,Laboratory of mass spectrometry, Chemistry, Liège, Belgium
    5. GIGA proteomic facility, Uliege, GIGA, Liège, Belgium
      18:08-18:14 DOP081: Genital granulomatosis in Crohn`s Disease: Results of the ECCO CONFER study
    F. Dederichs, I. Iesalnieks2, M. Sladek3, C. Tzivinikos4, R. Hansen5, C. Muñoz6, P. Pavli7, M. Cavicchi8, V. Abitbol9, J.-F. Rahier10, S. Vavricka11, K. Katsanos12, E. Domènech13, 14
    1.
    Kath. Krankenhaus Hagen, Hagen, Germany
    2. Klinikum Bogenhausen, München, Germany
    3. Jagiellonian University Medical College, Krakow, Poland
    4.
    Royal London Hospital, London, United Kingdom
    5. Royal Hospital for Children, Glasgow, United Kingdom
    6. Villafranca del Hospital Universitario de Basurto, Bilbao, Spain
    7. Canberra Hospital, Canberra, Australia
    8. Cabinet Medical Créteil, Paris, France
    9. Cochin Hospital, Paris, France
    10. CHU Dinant-Godinne, Department of Gastroenterology, Yvoir, Belgium
    11. Triemli Hospital, Zürich, Switzerland
    12. University and Medical School of Ioannina, Ioannina, Greece
    13. Hospital Universitari Germans Trias I Pujol, Badalona, Spain
    14. CIBEREHD, Madrid, Spain